Prostate cancer is often initially suspected on abdominal ultrasound in middle to older patients with urinary signs of straining and occasionally issues passing stools due to sublumbar lymph node enlargement. Changes noted on ultrasound of the prostate including the nodules, mineralization, and generalized prostate enlargement may be indicative of prostatic neoplasia (cancer). An ultrasound-guided FNA cytology or biopsy may help determine a diagnosis. Common locations for tumor spread include sublumbar lymph nodes under the spine and the pelvic/vertebral bones. Mitoxantrone chemotherapy is administered intravenously every 3 weeks. Carboplatin is another chemotherapeutic administered intravenously every 3 weeks. The recommended treatment for prostatic carcinoma involves non-steroidal anti-inflammatory medication (piroxicam, rimadyl, etc) and systemic chemotherapy. The prognosis without chemotherapy or NSAIDS is typically less than 1-2 months and the prognosis with therapy is approximately 6-8 months or less in patients with prostate carcinoma if the patient responds. Surgery is not recommended due to the high morbidity rate since the prostate in dogs wraps around the entire urethra and since prostatic carcinomas tend to metastasize or spread. Radiation to the prostate has a high risk of side effects and the possibility of strictures/scarring is very high. Radiation is primarily used if there are bone lesions to help with pain control. Urethral stenting is a palliative treatment and may only help 1-2 months in the event the patient can no longer urinate due to urethral blockage or lymph node compression.
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Randhurst Animal Hospital
212 East Rand Rd., Mt. Prospect, IL 60056
Veterinarians serving Mt Prospect, Des Plaines, Arlington Heights, Northbrook, Glenview, Morton Grove, Rolling Meadows, Wheeling, Prospect Heights, Palatine and surrounding areas
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