Randhurst Animal Hospital

Formerly Des Plaines Family Pet Clinic

847-398-5800

212 East Rand Rd., Mt. Prospect, IL 60056

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Mon - Fri: 8am • 7pm
Sat: 9am • 2pm
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HomeSmall Animal Veterinary ServicesVeterinary Tumors

Veterinary Tumors

Lymphoma, Canine

Lymphoma is a type of cancer involving an increased proliferation of a type of white blood cell, called a lymphocyte, which originates outside the bone marrow and is released into systemic circulation. Chemotherapy is the recommended treatment for dogs with lymphoma and the majority of patients will be able to clinically attain a complete remission. There are several chemotherapy protocols available, which have proven effectiveness for this disease. In many cases, we will start with an induction phase, at which time higher doses of chemotherapy are administered, followed by a maintenance phase, which often involves administering low doses of chemotherapy (most commonly oral cyclophosphamide or chlorambucil) at home. For the induction phase of chemotherapy, a protocol consisting of vincristine, cyclophosphamide, and doxorubicin along with prednisone has shown the longest remission times. L-asparaginase is a fast-acting chemotherapeutic, which may be administered at the start of the induction therapies in order to treat the disease rapidly. Generally remission times for patients with stage 5 lymphoma (skin, eye, GI, ect. Involvement), liver involvement, T-cell lymphoma, that are sick at diagnosis (substage b), or with hypercalcemia are around 6-8 months vs with stage 4 spleen involvement or less that are feeling well at diagnosis (substage a), and B-cell type, which are approximately 12-14 months with the 25 week or 19 week protocol. If we administer Adriamycin chemotherapy (strongest agent in the protocol) as a single agent every 2-3 weeks for 5-6 treatments, remission times are approximately 8-10 months. We may administer CCNU (Lomustine) orally every 2-3 weeks for 5-6 treatments and remission times with this protocol average around 4-6 months, but we would prefer to administer the CCNU as a rescue agent if Ash fails the other protocols. Approximately 80% of patients with lymphoma will respond to the chemotherapy protocol. However, remission times vary depending on the patient and the overall stage of their disease. With prednisone steroid alone, the prognosis is only 1-2 months on average

ONCOLOGY SECTION


Tumor Types

Veterinary Oncologist at Randhurst Animal Hospital

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